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PET Scans After Cancer Treatment | Choosing Wisely". www.choosingwisely.org. June 2014 . Retrieved 1 April 2019. Brain pathologies such as Alzheimer's disease greatly decrease brain metabolism of both glucose and oxygen in tandem. Therefore 18F-FDG PET of the brain may also be used to successfully differentiate Alzheimer's disease from other dementing processes, and also to make early diagnoses of Alzheimer's disease. The advantage of 18F-FDG PET for these uses is its much wider availability. Some 18F based radioactive tracers used for Alzheimer's include florbetapir, flutemetamol, PiB and florbetaben, which are all used to detect amyloid-beta plaques (a potential biomarker for Alzheimer's) in the brain. [17] Chapter 9 Occupational Exposure to Radiation" (PDF). Radiation, People and the Environment. IAEA. pp.39–42. Archived from the original (PDF) on 5 July 2008.

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Willett R, Harmany Z, Marcia R (2010). "Poisson image reconstruction with total variation regularization". 17th IEEE International Conference on Image Processing. pp.4177–4180. CiteSeerX 10.1.1.175.3149. doi: 10.1109/ICIP.2010.5649600. ISBN 978-1-4244-7992-4. S2CID 246589. A Vital Legacy: Biological and Environmental Research in the Atomic Age (Report). U.S. Department of Energy, The Office of Biological and Environmental Research. September 2010. pp.25–26. PET Scan: PET/CT History". Petscaninfo.com. Archived from the original on 14 April 2012 . Retrieved 13 August 2012.This section needs to be updated. Please help update this article to reflect recent events or newly available information. ( February 2018) Anand, Keshav; Sabbagh, Marwan (January 2017). "Amyloid Imaging: Poised for Integration into Medical Practice". Neurotherapeutics. 14 (1): 54–61. doi: 10.1007/s13311-016-0474-y. PMC 5233621. PMID 27571940.

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PET scanners work by detecting the radiation given off by a substance injected into your arm called a radiotracer as it collects in different parts of your body. The image resolution of nuclear medicine images may not be as high as that of CT or MRI. However, nuclear medicine scans are more sensitive for a variety of indications. The functional information they yield is often unobtainable using other imaging techniques.

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Compared with CT scans and magnetic resonance images (MRIs), PET images appear much blurrier or noisier, due to the relatively limited number of photons that can be collected during an imaging study. In addition, detector resolution is poorer due to the detector physics. X-ray CT scanners can easily resolve points < 1 mm in size, whereas PET scanners cannot reliably resolve point sources < 4 to 5 mm at best, and closer to 10 mm in practice. However, this does not impair their high sensitivity to focal tracer concentrations or their usefulness in accurate quantitative functional imaging. Ordinary x-rayexams pass x-rays through the body to create an image. Nuclear medicine uses radioactive materials called radiopharmaceuticals or radiotracers. Your doctor typically injects this material into your bloodstream. Or you may swallow it or inhale it as a gas. The material accumulates in the area under examination, where it gives off gamma rays. Special cameras detect this energy and, with the help of a computer, create pictures that detail how your organs and tissues look and function. Birkin E, Moore K, Huang C et al. Determinants of Physiological Uptake of 18F-Fluorodeoxyglucose in Palatine Tonsils. Medicine (Baltimore). 2018;97(24):e11040. doi:10.1097/MD.0000000000011040 - Pubmed PET scans are particularly helpful for investigating confirmed cases of cancer to determine how far the cancer has spread and how well it's responding to treatment. Khan FR, Henderson JM (2013). "Deep Brain Stimulation Surgical Techniques". In Lozano AM, Hallet M (eds.). Brain Stimulation: Handbook of Clinical Neurology. Vol.116. Amsterdam: Elsevier. pp.28–30. doi: 10.1016/B978-0-444-53497-2.00003-6. ISBN 9780444534972. PMID 24112882.

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a b ARSAC - Notes for Guidance on the Clinical Administration of Radiopharmaceuticals and use of Sealed Sources (March 2018 p.35) Except for intravenous injections, most nuclear medicine procedures are painless. Reports of significant discomfort or side effects are rare.Altered blood sugar or blood insulin levels may adversely affect the test results of diabetic patients or patients who have eaten a few hours prior to the exam. PET scans are sometimes used to help plan operations, such as a coronary artery bypass graft or brain surgery for epilepsy. Brownell GL, Burnham CA, Hoop Jr B, Bohning DE (August 1945). Quantitative dynamic studies using short-lived radioisotopes and positron detection. Symposium on Dynamic Studies with Radioisotopes in Medicine. Rotterdam: IAEA Vienna. pp.161–172. A coronary calcium scan is a CT scan of the heart that doctors use to detect and measure calcium-containing plaque in someone's arteries. READ MORE In a PET scan, a machine detects the radiation that a radiotracer emits. A radiotracer consists of radioactive material tagged to a natural chemical, such as glucose.