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This medicine contains less than 1 mmol sodium (23 mg) per 5ml, that is to say essentially 'sodium-free'. The NHS says that babies aged 3-5 months can have a maximum of 2.5ml of ibuprofen three times in 24 hours (3-4 times in 24 hours if they're aged 6-11 months). Although paracetamol is considered safe for use during breastfeeding, it is not known if phenylephrine passes into breast milk, or its effect on a nursing infant. When taken by mouth, decongestants such as phenylephrine can also temporarily decrease the production of breast milk with just one or two doses. For this reason, this medicine is best avoided by mothers who are breastfeeding. Ask your doctor or pharmacist for further advice. Phenylephrine overdose is likely to result in: nervousness, headache, dizziness, insomnia, increased blood pressure, nausea, vomiting, reflex bradycardia, mydriasis, acute angle closure glaucoma (most likely to occur in those with closed angle glaucoma), tachycardia, palpitations, allergic reactions (e.g. rash, urticaria, allergic dermatitis), dysuria, urinary retention (most likely to occur in those with bladder outlet obstruction, such as prostatic hypertrophy). You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.
Lemsip cold & flu sachets contain two active ingredients, the painkiller paracetamol (650mg) and a decongestant called phenylephrine hydrochloride (10mg). Get immediate medical advice if you or someone you know takes too much paracetamol, even if you feel well, because of the risk of delayed, serious liver damage. Don't give more than four paracetamol doses in 24 hours. This means you might have to wait up to six hours between doses. Patients with rare hereditary problems of fructose intolerance, glucose- galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.
If you forget to take it
It's fine to take Lemsip max cold & flu sachets with plain ibuprofen or aspirin (assuming these are appropriate for you). However, don't take them with co-codamol, co-dydramol or Tramacet because these contain paracetamol. Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24 hours from ingestion should be discussed with the NPIS or a liver unit. Haemolytic anaemia (in patients with glucose-6-phosphate dehydrogenase [G6PD] deficiency): Haemolysis has been reported in patients with G6PD deficiency, with use of paracetamol in overdose. Abnormalities of glucose metabolism and metabolic acidosis may occur. Blood bilirubin, hepatic enzymes, INR, prothrombin time, blood phosphate and blood lactate may be increased. https://www.mhra.gov.uk/Howweregulate/Medicines/Licensingofmedicines/Informationforlicenceapplicants/Guidance/OverdosesectionsofSPCs/Genericoverdosesections/Paracetamol/index.htm
It is safe to take Lemsip cold & flu sachets with ibuprofen or aspirin. However, do not take them with co-codamol, co-dydramol or Tramacet because these contain paracetamol. kg to 30mg/kg as a single dose up to a maximum of 1g. Then 15mg/kg to 20mg/kg every 4 to 6 hours when necessary, up to a maximum of 75mg/kg (4g) daily in divided doses.Summary of Product Characteristics: Calpol Infant suspension sachets. McNeil Products Ltd. Revised November 2014 Summary of Product Characteristics: Paracetamol Oral solution. Mercury Pharmaceuticals Ltd. Revised October 2013. Paracetamol is excreted in breast milk but not in a clinically significant amount. Available published data do not contraindicate breastfeeding.
An additive used in food products, drugs and cosmetics. Some reports have associated these ingredients with skin irritation. Summary of Product Characteristics: Calpol Six Plus suspension. McNeil Products Ltd. Revised November 2014 A food additive. Allergic reactions might occur in patients who suffer from asthma or those sensitive to aspirin. Each sachet contains approximately 2.6g of carbohydrate. Patients with rare hereditary problems of fructose intolerance, glucose- galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.
Taking paracetamol with other painkillers
Care is advised in the administration of paracetamol to patients with severe renal impairment or severe hepatic impairment. The hazards of overdose are greater in those with non-cirrhotic alcoholic liver disease. The use of drugs that induce hepatic microsomal enzymes, such as anticonvulsants and oral contraceptives, may increase the extent of metabolism of paracetamol, resulting in reduced plasma concentrations of the drug and a faster elimination rate. a) Is on long-term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes, or Talk to a doctor at once if your child takes too much of this medicine, even if they seem well (label).
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