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Aerials (Rifts Book 1)

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T1 - Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models Morales E, Gascon M, Martinez D, Casas M, Ballester F, Rodríguez-Bernal CL, Ibarluzea J, Marina LS, Espada M, Goñi F. Associations between blood persistent organic pollutants and 25-hydroxyvitamin D3 in pregnancy. Environment International. 2013; 57:34–41. [ PubMed] [ Google Scholar] Rhainds M, Levallois P, Dewailly É, Ayotte P. Lead, mercury, and organochlorine compound levels in cord blood in Quebec, Canada. Archives of Environmental Health: An International Journal. 1999; 54(1):40–47. [ PubMed] [ Google Scholar]

Muir DC, Howard PH. Are there other persistent organic pollutants? A challenge for environmental chemists. Environmental Science & Technology. 2006; 40(23):7157–7166. [ PubMed] [ Google Scholar]

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Olshan AF. Meeting report: the use of newborn blood spots in environmental research: opportunities and challenges. Environmental Health Perspectives. 2007; 115(12):1767–1779. [ PMC free article] [ PubMed] [ Google Scholar] Councillor Brawn explained: “As you would expect LAL [Live Active Leisure] carries the usual fully comprehensive insurance that any other commercial organisation would have. However, following severe flooding of both Bell’s and the Perth Leisure Pool in August 2020, there is an exclusion on surface water flooding.

But just over a year later on Sunday, October 8, the gym and all ground floor areas – including the arena – suffered “considerable damage”. Wimmerová S, Lancz K, Tihányi J, Šovčíková E, Kočan A, Drobná B, Palkovičová L’, Jurečková D, Fabišiková A, Čonka K. Half-lives of serum PCB congener concentrations in environmentally exposed early adolescents. Chemosphere. 2011; 82(5):687–691. [ PubMed] [ Google Scholar] Live Active Leisure chief executive Paul Cromwell said: “Obviously we have experienced floods at Bell’s. That’s widely known. Our last most significant one was 2020 which as everyone will remember was described as a one in 100-year flood – but here we are again.” Jaraczewska K, Lulek J, Covaci A, Voorspoels S, Kaluba-Skotarczak A, Drews K, Schepens P. Distribution of polychlorinated biphenyls, organochlorine pesticides and polybrominated diphenyl ethers in human umbilical cord serum, maternal serum and milk from Wielkopolska region, Poland. Science of the total environment. 2006; 372(1):20–31. [ PubMed] [ Google Scholar] Sun P, Blanchard P, Brice K, Hites RA. Atmospheric organochlorine pesticide concentrations near the Great Lakes: temporal and spatial trends. Environmental Science & Technology. 2006; 40(21):6587–6593. [ PubMed] [ Google Scholar]Adam BW, Alexander JR, Smith SJ, Chace DH, Loeber JG, Elvers L, Hannon WH. Recoveries of phenylalanine from two sets of dried-blood-spot reference materials: prediction from hematocrit, spot volume, and paper matrix. Clinical Chemistry. 2000; 46(1):126–128. [ PubMed] [ Google Scholar] Mr Cromwell said: “Unfortunately the volume of water overwhelmed the arrangements that we had in place that particular weekend.” But Live Active Leisure board member councillor Brawn – and fellow residents who provided distressing deputations to the committee – believe the failure to close the floodgates in time was more than a contributory factor. Venier M, Hites RA. Time trend analysis of atmospheric POPs concentrations in the Great Lakes region since 1990. Environmental Science & Technology. 2010; 44(21):8050–8055. [ PubMed] [ Google Scholar] Louis GMB, Germaine M, Hediger ML, Bell EM, Kus CA, Sundaram R, McLain AC, Yeung E, Hills EA, Thoma ME. Methodology for establishing a population-based birth cohort focusing on couple fertility and children’s development, the Upstate KIDS Study. Paediatric and Perinatal Epidemiology. 2014; 28(3):191–202. [ PMC free article] [ PubMed] [ Google Scholar]

Numerous studies have shown that POPs elicit adverse health effects in humans, including disruption of endocrine systems as well as reproductive and immunological effects ( Ha et al. 2007; Morales et al. 2013; Tsuji et al. 2013). For example, serum concentrations of PCBs, p,p′-DDE, and HCB were associated with reduced thyroid hormone levels in adult men ( Meeker et al. 2007). High plasma HCB and PCB concentrations were significantly associated with the risk of developing type 2 diabetes ( Wu et al. 2013). An increased risk for obesity was associated with prenatal exposure to PCBs and DDE in children ( Valvi et al. 2012). In comparison with adults, fetuses, newborns, and infants are more sensitive to the effects of environmental chemicals ( Lignell et al. 2013). POPs have been shown to cross the maternal/trans-placental barrier ( Covaci et al. 2002; Jaraczewska et al. 2006). Owing to the administrative and/or legal restrictions in obtaining blood samples for research purposes, little is known regarding the levels of POPs in newborns. Ha M-H, Lee D-H, Jacobs DR., Jr Association between serum concentrations of persistent organic pollutants and self-reported cardiovascular disease prevalence: results from the National Health and Nutrition Examination Survey, 1999–2002. Environmental Health Perspectives. 2007; 115(8):1204–1209. [ PMC free article] [ PubMed] [ Google Scholar] Vizcaino E, Grimalt JO, Lopez-Espinosa M-J, Llop S, Rebagliato M, Ballester F. Maternal origin and other determinants of cord serum organochlorine compound concentrations in infants from the general population. Environmental Science & Technology. 2010; 44(16):6488–6495. [ PubMed] [ Google Scholar] A report by Perth and Kinross Council’s (PKC) chief executive Thomas Glen admitted floodgates at the North Inch were not closed in time during the extreme weather event on the weekend of October 7 and 8.

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Ma W, Kannan K, Wu Q, Bell EM, Druschel CM, Caggana M, Aldous KM. Analysis of polyfluoroalkyl substances and bisphenol A in dried blood spots by liquid chromatography tandem mass spectrometry. Analytical and Bioanalytical Chemistry. 2013a; 405:4127–4138. [ PubMed] [ Google Scholar] arena and squash courts – damaged; underfloor wood support damaged; office areas damaged; electrical equipment and circuitry damaged. The list goes on. Following the August 2020 flood changes were made to drainage, downpipes were moved and circulation areas were ramped to try and protect play areas.

His report reviewing the local impact of the extreme weather events in October 2023 – which went before PKC’s Scrutiny and Performance Committee on Wednesday November 22 – said this failure “may have contributed to the flooding of some properties”. Valvi D, Mendez MA, Martinez D, Grimalt JO, Torrent M, Sunyer J, Vrijheid M. Prenatal concentrations of polychlorinated biphenyls, DDE, and DDT and overweight in children: a prospective birth cohort study. Environmental health perspectives. 2012; 120(3):451–457. [ PMC free article] [ PubMed] [ Google Scholar] An electromechanical device that works with the help of an electromagnet is called an electric bell. In a classic bell, on applying an electric current, the to and fro movement of a small hammer on a gong would produce the sound of a bell. Thus, an electric bell is an electric device generally used for signalling the presence of a guest or visitor. Describing the “considerable” damage, councillor Brawn told the committee: “New gym equipment was damaged; floors to affected areas – especially the mainSpliethoff HM, Tao L, Shaver SM, Aldous KM, Pass KA, Kannan K, Eadon GA. Use of newborn screening program blood spots for exposure assessment: declining levels of perfluorinated compounds in New York State infants. Environmental Science & Technology. 2008; 42(14):5361–5367. [ PubMed] [ Google Scholar] Covaci A, Jorens P, Jacquemyn Y, Schepens P. Distribution of PCBs and organochlorine pesticides in umbilical cord and maternal serum. Science of the total environment. 2002; 298(1):45–53. [ PubMed] [ Google Scholar] la Marca G, Villanelli F, Malvagia S, Ombrone D, Funghini S, De Gaudio M, Fallani S, Cassetta MI, Novelli A, Chiappini E. Rapid and sensitive LC-MS/MS method for the analysis of antibiotic linezolid on dried blood spot. Journal of pharmaceutical and biomedical analysis. 2012; 67:86–91. [ PubMed] [ Google Scholar] Grandjean P, Budtz-Jørgensen E, Barr DB, Needham LL, Weihe P, Heinzow B. Elimination half-lives of poly chlorinated biphenyl congeners in children. Environmental Science & Technology. 2008; 42(18):6991–6996. [ PMC free article] [ PubMed] [ Google Scholar] In July 2022, Live Active Leisure opened its state-of-the-art 100-plus station gym Bell’s Sports Centre to the public.

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