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Though devil’s claw has not been studied extensively in humans, preliminary evidence suggests that it may be an alternative treatment for inflammatory conditions. Summary
Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999. When choosing a supplement, look for the concentration of harpagoside, an active compound in devil’s claw.
3 proven benefits of devil’s claw
In addition, a supplement called AINAT has been used as a remedy for osteoporosis. AINAT contains 300 mg of devil’s claw, as well as 200 mg of turmeric and 150 mg of bromelain — two other plant extracts believed to have anti-inflammatory effects ( 18). Baghdikian B, Lanhers MC, Fleurentin J, et al. An analytical study, anti-inflammatory and analgesic effects of Harpagophytum procumbens and Harpagophytum zeyheri. Planta Med 1997;63:171-6. View abstract.
Chrubasik, S. [Devil's claw extract as an example of the effectiveness of herbal analgesics]. Orthopade 2004;33:804-808. View abstract. Devil’s claw can be found as a concentrated extract, capsule, tablet or powder. It’s also used as an ingredient in herbal teas.
What is Devil’s Claw?
Jang MH, Lim S, Han SM, et al. Harpagophytum procumbens suppresses lipopolysaccharide-stimulated expressions of cyclooxygenase-2 and inducible nitric oxide synthase in fibroblast cell line L929. J Pharmacol Sci 2003;93:367-71. View abstract. Occhiuto, F., Circosta, C., Ragusa, S., Ficarra, P., and Costa, De Pasquale. A drug used in traditional medicine: Harpagophytum procumbens DC. IV. Effects on some isolated muscle preparations. J Ethnopharmacol. 1985;13:201-208. View abstract. Also do not take devil's claw without medical advice if you are using any of the following medications:
Ameye, L. G. and Chee, W. S. Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence. Arthritis Res Ther 2006;8:R127. View abstract. You can find devil’s claw supplements in the form of concentrated extracts and capsules, or ground into a fine powder. It’s also used as an ingredient in various herbal teas. Summary Tunmann P and Bauersfeld HJ. Über weitere Inhaltsstoffe der Wurzel von Harpagophytum procumbens DC. Arch Pharm (Weinheim) 1975;308:655-657.
Chantre P, Cappelaere A, Leblan D, et al. Efficacy and tolerance or Harpagophytum procumbens versus diacerhein in treatment of osteoarthritis. Phytomedicine 2000;7:177-83. View abstract. Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;18:2273-81. View abstract.