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Two of the most popular joint support supplements are Glucosamine, an amino sugar naturally concentrated in joint tissues, and Turmeric, a superfood spice rich with antioxidant, anti-inflammatory curcuminoids. Whether you are an athlete or simply looking for joint support, you might want to explore our multiple options below. Williams C, Ampat G. Glucosamine Sulfate. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Turmeric Dosage: a notably safe superfood with a notably poor oral bioavailability, turmeric in raw form requires a large dosage to work, which is why it’s best to take a potent turmeric extract (e.g., CurcuWIN®) a dosage of 250mg daily for general joint support.
These mixed recommendations may partially stem from the fact that the manufacturer and type of the supplements can result in different study results. For example, pharmaceutical-grade varieties appear more effective compared with over-the-counter options ( 4, 5). SummaryRespectively, the ideal forms of both supplements are plant-based glucosamine sulfate 2KCl and CurcuWIN®, a premium, patented turmeric extract standardized to 20% curcuminoids and designed to make curcumin 46X more absorbable. Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Martel-Pelletier J et al. Cyclooxygenase-2 and prostaglandins in articular tissues. Semin Arthritis Rheum. 2003 Dec; 33(3): 155-67.
Though more direct and specific in its bioactivities, compared to turmeric’s multiple health benefits, glucosamine comes with a number of joint-related benefits, including: Chondrocyte Support Professionals: from sitting at a desk to strenuous manual labor, repetitive work-related motions may encourage poor posture and strain joints. Instead, look for a joint support formula that supplies glucosamine and turmeric at the following dosages: Tech Workers: texting, typing, tapping—though the life of a tech enthusiast seems fairly injury-free, tech usage does accumulate a significant amount of connective tissue strain. Finally, a 2 1/2-year study in 407 women with overweight ages 50–60 found 1,500 mg/day of glucosamine sulfate to significantly decrease the risk of knee osteoarthritis compared with a placebo, suggesting that it may work as a preventive therapy ( 9). ChondroitinBy eliminating the effect of advanced glycation end-products, turmeric’s curcumin offers significant protective advantages for joint connective tissues, as well as for the cardiometabolic system and brain health. Is It Safe to Take Glucosamine and Turmeric Together? A review must be well-formatted to make reading easier by using multiple paragraphs and avoiding caps.
If that weren’t enough, it also contains various minerals that support joint health plus ginger extract. Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials https://www.liebertpub.com/doi/10.1089/jmf.2016.3705 A: The manufacturers have not mentioned any side effects. However, ingredients such as glucosamine and chondroitin have side effects. Glucosamine may cause heartburn, nausea, and diarrhea while MSM may cause swelling, fatigue, insomnia, and headache. If this sounds like a problem you might also have, you might like to opt for the water soluble Holland & Barrett MSM Powder. Jointace has also developed a patch to get some of these same ingredients to your body via a different method of absorption.
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However, keep in mind that glucosamine is commonly derived from chitin — a compound found in shellfish. Therefore, those with a shellfish allergy should read the label carefully and opt for varieties made from cows or pigs ( 17). However, some popular turmeric extract brands, namely CurcuWIN®, help increase the potency of turmeric’s bioactive curcuminoids. Combined with chondroitin, glucosamine has been shown in research to help mitigate synovial fluid inflammation to provide “efficient pain relief in similar level with tramadol, a narcotic analgesic.” The Combined Benefits of Glucosamine + Chondroitin
The joint pain formula is touted to promote flexibility, ease joint stiffness, lubricate joints, and nourish the joints. Though the two can be taken separately, glucosamine and chondroitin are commonly taken as a single supplement. This combination has been more extensively studied. Similarly, a 2015 sponsored study showed that combining 1,500 mg of glucosamine hydrochloride with 1,200 mg of chondroitin sulfate effectively reduced knee osteoarthritis pain, stiffness, and swelling compared with 200 mg of the osteoarthritis NSAID celecoxib ( 15). But if you had to choose between the two, which is better for joint health: glucosamine or turmeric? Of the two, glucosamine seems more focused on improving joint health, whereas turmeric is a more multi-purpose “superfood.” Both are generally safe for daily supplementation. And both improve joint health and flexibility in their own ways.Glucosamine, chondroitin, and MSM are generally safe but may interact with blood thinners and acetaminophen and interfere with blood sugar and eye pressure. Desai SJ et al. Mechanisms of phytonutrient modulation of Cyclooxygenase-2 (COX-2) and inflammation related to cancer. Nutr Cancer. 2018 Apr; 70(3): 350-375. Though there isn’t much research on the specific combination of glucosamine and turmeric, it’s important to take minimally effective dosages of each, to ensure enough formula space for all joint-support ingredients to work. Optimal Dosages of Turmeric and Glucosamine N-acetyl glucosamine (NAG). Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Oct. 24, 2020.
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