Calmex Capsules

Product Information

The problem with dietary management to control anxiety, is that it requires adhering to the above, strict regime. Also, for this regime to work optimally, the dog would be required to have high, initial levels of tryptophan which is dependent on the quality of the protein meal. A tryptophan containing supplement would be more ideal. One other factor to consider is that controlling the diet would not be suitable for acute situations as preparation is required at least 2 hours in advance. Pharmaceuticals

The reliability of sedative drugs when administered orally is unreliable and, as such, high doses of the drug may be required. Using high doses however, can cause systemic effects such as hypervolemia (increased blood-fluid volume), hyperexcitability and extrapyrimidal side effects such as akinesia (an inability to move) or akathisia (an inability to remain still). Combined in this formulation promotes relaxation in dogs. It is a supplement for the dog's diet, not something which should replace their normal nutrition. In other words, it is a nutritional supplement with a calming effect, it is not a complete food for dogs.Some experts, however, argue that causality between the adverse effect and use of P. methysticum has not been established with sufficient certainty. In several cases, liver damage could have been due to other drugs or alcohol taken concomitantly. In other instances, excessive and prolonged doses of P. methysticum had been used (Ernst E, 2007).

Dogs which have been adopted from animal shelters are often prone to anxiety. They may have experienced trauma, neglect, abandonment or abuse which leaves them feeling scared and insecure. For this reason, otherwise normal stimuli can often cause exaggerated responses. Learn more in our article on reasons a dog is stressed out a lot. Travelling– Some dogs are quite happy to travel in a vehicle, some even enjoy it! However, there are a proportion of dogs that will experience varying levels of distress and anxiety from travelling. Anxiety is a natural, emotional response to a potentially harmful stimulus (also known as a stressor). Fear inducing stimuli initiate two pathways within the brain, these pathways (discovered by Joseph LeDoux) are sometimes referred to as the ‘High Road’ and the ‘Low Road’. Another nutraceutical product is CALMEX ®, a unique combination of two amino acids, a psychoactive plant extract and numerous B Vitamins. These ingredients produce a synergistic effect by modulating neurotransmitter production and multiple other pathways within the brain. The result is acute anxiolysis and mild sedation. CALMEX ® can be used alone or in conjunction with behavioural programmes. By nature, dogs are social animals, this means many can become stressed or experience anxiety when they are left alone – for instance, when their owner leaves for work.For best results CALMEX® should be administered for three days prior to a stressful event. If required, double the recommended amount can be given 30-60 minutes prior to an acute stressor. A signal is also simultaneously propagated along the ‘High Road’. The signal again, travels from the thalamus to the amygdala; however, it travels via the sensory cortex and the hippocampus. The result of this is the ability to associate the stressor with previous learned experiences, thus a more rational response to the stressor is produced (Neilson JC, 2002). CALMEX® is a nutritional supplement for dogs to help support normal healthy composure. Suitable in situations such as if your dog is nervous coming to the vets or the groomer, stressed on car journeys, home alone or doesn’t like noises, including fireworks. Or to make the potentially stressful experience of going into kennels - a happier, more relaxed one.

When exposed to a stressor, the activity of the involved neurotransmitter pathway is altered. The activity of the serotonergic and GABAnergic pathways are decreased whilst the activity of noradrenaline pathways are increased. Situational phobias can arise for a number of reasons from varying environments and stimuli. Typically, such phobias develop due to a previous negative association with stimuli. They can also arise when a dog is exposed to a new situation or for seemingly no reason at all. Calmex is a calming supplement to help manage stress and anxiety in dogs and cats. It consists of a specially blended feed to help promote relaxed behaviour in dogs and cats experiencing behavioural problems as a result of their surroundings or environment. It is fast-acting. The clinical signs of a dog suffering from a situational phobia are the same, no matter what the trigger stimulus is. These signs can include any of the following; vocalisation, trembling, urination/defecation, attempted escape, reluctance to leave the owner’s side or in rare cases, aggression. Calmex for cats is a liquid which can be administered directly into your cat’s mouth, or mixed with food.

CALMEX ® also includes a psychoactive plant extract, Piper methysticum, which, when taken orally, has been used for thousands of years for the treatment of anxiety, stress and insomnia. P.methysticum, or Kava as it is commonly known, can also be applied topically to produce analgesic and wound healing effects. When comfortable and happy, cats mark their territory as familiar by rubbing their face against corners, furniture, people or other cats at home. By doing this, they release a pheromone, or “happy message”. When present in the environment, these “happy messages” provide reassurance to all cats. Feliway is a form of these pheromones. The sale of P. methysticum for oral use in humans was prohibited in the UK in 2003 based on theories that there may be an associated risk between hepatotoxicity and Piper methysticum.