Assignment (The Cerenia Chronicles)

Product Information

The safety of Cerenia has not been established in dogs less than 16 weeks of age and in pregnant or lactating bitches. Use only according to a risk benefit assessment by the responsible veterinary surgeon.

Do not use this veterinary medicinal product after the expiry date which is stated on the blister after EXP.

Cerenia should be used with caution in animals suffering from or with a predisposition for heart diseases. Cerenia should not be used concomitantly with Ca-channel antagonists as maropitant has affinity to Ca-channels. It was approved by the FDA in the United States in 2007 for use in dogs, then in 2012 for cats. Cerenia is now widely used for cats in veterinary clinics around the world. How Cerenia Works Ask your veterinary surgeon how to dispose of medicines no longer required. These measures should help to protect the environment.

Vomiting can be associated with serious, severely debilitating conditions including gastrointestinal obstructions; therefore, appropriate diagnostic evaluations should be employed. Substance P is the key neurotransmitter involved in vomiting, and it’s found at all three of these locations. Cerenia has a similar structure to Substance P, allowing it to bind to the NK1 receptors in the same way as Substance P, but without causing the same stimulation.

How Cerenia Works

The use of Cerenia has not been studied in pregnant or lactating cats and it should not be used in kittens under sixteen weeks of age. More specifically, Cerenia is a neurokinin-1 (NK1) receptor antagonist that stops substance P from binding to NK1 receptors. NK1 receptors are intimately involved in the initiation of vomiting. As well as in the chemoreceptor trigger zone (CRTZ) and the vomiting centre in the brain, they are found in the vagus nerve (close to the digestive tract). Our survey will give users of the Compendium the opportunity to say how they think we can improve it to assist them in prescribing veterinary medicines and advising animal keepers on their use. We look forward to getting your views”. Holding one side of the cut firmly, pull the other side towards the centre of the blister until the tablet is visible.