AREDS2 VISION DEFENDER AMD Supplement: Lutein, Zeaxanthin, Zinc, Vitamin E – AREDS 2 Eye Vitamins, Minerals, Nutrients for Eyes. 3 Months Supply (90 tablets) One-A-Day Vegan Eye Supplement. Made in UK

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Some scientists believe that another macular carotenoid, meso-zeaxanthin, is also important for macular health. It is made by the body from lutein. It was not tested in the AREDS trials and not all scientists agree on its significance. More research is needed in this area.

Be aware of:Supplements containing ALA (another omega-3 fatty acid) instead of DHA/EPA. ALA is found mainly in plant oils such as flaxseed, and only very small amounts are converted by the body to useful EPA and then to DHA. Practically, this means DHA/EPA needs to be consumed directly from food or supplements. Note that studies of health benefits of omega-3 generally involve using DHA/EPA omega-3 supplements (not ALA omega-3). The AREDS study found that ‘people at high risk for developing advanced AMD—those with intermediate AMD, and those with advanced AMD in one eye only—reduced their risk of developing advanced (AMD) by about 25% when treated with a combination of antioxidants and zinc + copper” as found in VisuBright – making it a comprehensive solution for proactive AMD support.Eye Disease Case-Control Study Group. Antioxidant status and neovascular age-related macular degeneration. Arch Ophthalmol. 1993 Jan;111(1):104-9. doi: 10.1001/archopht.1993.01090010108035. https://pubmed.ncbi.nlm.nih.gov/7678730/ LUTEIN & ZEAXANTHIN - The only two macular carotenoids recommended by the latest AREDS 2 research. Supporting healthy pigmentation and therefore protection against wear and tear of the macula. The third macula pigment meso-zeaxanthin is shown to be created in the eye once you have good dietary intake of lutein and zeaxanthin. It is thought too much cooking may destroy it. Cooking with oil or fat may help with absorption into the body. However, research is ongoing. Drusen are made up of cellular waste materials that collect under the retina. These white or yellow deposits are a common early sign of AMD. The AREDS2 supplements are not available on prescription. Vitamin supplementation with AREDS2 Vitamin combinations such as VisuBright is an easy way to be proactive about your eye health and reduce the risk of AMD progression and associated vision loss.

Some studies suggest very light cooking may increase the bioavailability of lutein; that is the ease with which the body can absorb the lutein. Be aware of:Supplements NOT containing standardised amounts of the active compounds anthocyanins and procyanidins, particularly if the amounts are not shown at all, as the content of the active compounds would be unknown. Mares-Perlman JA, Fisher AI, et al. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Am J Epidemiol. 2001 Mar 1;153(5):424-32. doi: 10.1093/aje/153.5.424. https://pubmed.ncbi.nlm.nih.gov/11226974/

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Diet is important because certain nutrients protect the body from damaging substances called oxidants.

Gaziano JM, Glynn RJ, et al. Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA. 2009 Jan 7;301(1):52-62. doi: 10.1001/jama.2008.862. https://pubmed.ncbi.nlm.nih.gov/19066368/ Gorusupudi A, Nelson K, Bernstein PS. The Age-Related Eye Disease 2 Study: Micronutrients in the treatment of macular degeneration. Adv Nutr. 2017;8(1):40-53. doi:10.3945/an.116.013177 With VisuBright, you can take control of your eye health and have peace of mind knowing that you're getting a formula based on the latest research and evidence. We are committed to supporting your nutritional needs and helping you maintain your vision and quality of life, so that you can continue to see the beauty in the world around you. It is therefore scientifically one the best nutrient combinations for the maintenance of macular heath. AREDS found that people diagnosed as being at medium or high risk of progression of AMD, who took the “AREDS formula” used on the trial, reduced their progression by 25 per cent. However, the beneficial effect of taking the supplement was not significant in those with a diagnosis of early-stage low risk AMD.

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Play a vital role in retinal cell survival and are crucial for the normal functioning of antioxidant enzymes

In 1994, the Alpha-Tocopherol, Beta Carotene (ATBC) trial found a 35% reduced risk of prostate cancer in men taking 50 mg of vitamin E (synthetic, equivalent to 56 IU) daily for a follow-up of six years. ( reference 8) ENHANCED AREDS2 FORMULA, ENHANCED EYE HEALTH CARE - This special eye supplement provides the EXACT gold standard AREDS2 formula (Lutein 10mg, Zeaxanthin 2mg, Vitamin C 500mg, Vitamin E 400IU, Zinc 25mg, Copper 2mg), PLUS the added power of Meso-Zeaxanthin 10mg. By adding the ‘missing’ ingredient Meso-Zeaxanthin to the AREDS2 formula, Vision Defender PLUS provides all the carotenoids found in the eye, thus 'completing' a well established formula and bringing superior eye health benefits. Zeaxanthin 2 mg: Zeaxanthin is also a carotenoid.The body does not produce its own zeaxanthin; it must obtain zeaxanthin from the diet as well. New blood vessel growth is medically known as “neovascularisation”. Neovascularisation can cause a lot of damage to your macula and can eventually lead to scarring. Both the new blood vessels and the scarring cause damage to your central vision and may lead to a blank patch in the centre of your sight. PREMIUM QUALITY, VEGAN AND VEGETARIAN FRIENDLY – This eyesight supplement is made in the UK using top-grade ingredients to strict GMP (Good Manufacturing Practice) standards in MHRA inspected facilities, so you can be assured that this is a superior quality eye supplement. Specially made to be suitable for vegan and vegetarians, all ingredients are from vegetable sources and are free from artificial preservatives, colours, flavours, lactose, gluten and GMO. Cruelty-free: Not tested on animals.

While it is important to eat a wide range of foods, the vegetables that have the highest amount of lutein are: Talk to your GP before taking supplements or making major changes to your diet, especially if you take other medications. People who take warfarin, for example, may need to avoid high doses of omega-3 as it thins the blood. Vitamins E and K may also interact with medicines like warfarin and aspirin. Dry AMD is the more common type of AMD. It develops very slowly and causes a gradual change in your central vision. Dry AMD usually takes a long time – often years, to get to its final stage. At its final stage, dry AMD causes a blank patch in the centre of your vision in both of your eyes. It doesn’t affect your peripheral (side) vision, so it never leads to total blindness.